UCSF Autism Studies

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University of California San Francisco

Age Group: 2 - 5 yrs. old, 6 - 12 yrs. old, 13-18 yrs. old

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CBD study: 12 weeks of study medication (cannabidiol (Epidyolex) or placebo) for ages 6-17 to evaluate change in symptoms in Autism Spectrum Disorder

Assessment for the diagnosis of autism and to assess the severity of autism
3 clinic visits to UCSF and 7 telephone visits
There will be blood draws and ECG
Exclusion criteria

ADHD or other diagnoses that dominates the clinical presentation Axial study (Gut Metabolite Supplementation): 8 weeks trial of study medication or placebo for ages 13-17 with GI symptoms to evaluate the effects of this supplement, which coats irritating metabolites in the gut to attempt to reduce irritability in Autism.

6 clinic visits to UCSF and 3 phone visits
Exclusion criteria : history of inflammatory bowel disease, history of diabetes, certain medications.
There will be blood draws and ECG

ANCHOR (Irritability Associated with ASD; Otsuka) Study: Brexpiprazole is a recently developed medication to reduce irritability associated with Autism: Treatment with study medication (medication or placebo) for 8 weeks for ages 5-17 followed by extension study (on medication) for 26 weeks.

Combination of 4 clinic visits at UCSF, 4 virtual visits and one phone visit.
There will be blood draws, ECG and testing.

1111 Franklin Street
Oakland, CA 94607

(415) 476-7803

felicia.widjaja@ucsf.edu

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